Cysticlean - When your urinary health is an issue again and again ...

What is the proof?

Studies on Cranberry

• Cochrane institute has suggested that the ingestion of cranberry extracts will help to prevent urinary low tract infections caused by Escherichia coli.
• Studies :

1. In-vitro and in-vivo evidence of dose-dependent decrease of uropathogenic Escherichia coli virulence after consumption of commercial Vaccinium macrocarpon (cranberry) capsules !.-P. Ullviglle1, G. BOll, C. CombesCllre, H. Botto and A. Sotto? Clin Microbio lnfect 2008; 14: 350-355
2. SAFETY AND EFFICACY OF CRANBERRY (Vaccinium Macrocarpon) DURING PREGNANCY AND LACTATION.Jean-Jacques Dugoua, Dugald Seely, Daniel Perri, Edward Mills, Gideon Koren. Can J Clin Pharmacol Vol 15 (1) Winter 2008:e80-e86; January 18, 2008
3. Daily Cranberry Juice for the Prevention of Asymptomatic Bacteriuria in Pregnancy: A Randomized, Controlled Pilot Study Deborah A. Wing,*,? Pamela J. Rumney, Christine W. Preslicka and Judith H. Cheng. THE JOURNAL OF UROLOGY Vol. 180, 1367-1372, October 2008.
4. Cranberries for preventing urinary tract infections (Review) Jepson RG, Craig JC The Cochrane Library 2008, Issue 4

Studies identifying that the preventative action of cranberry is directly related to the level of PAC

1. EFECTO DEL ARANDANO AMERICANO (CYSTICLEANR)? SOBRE LA ADHERENCIA DE ESCHERICHIA COLI A CELULAS EPITELIALES DE VEJIGA. ESTUDIO IN VITRO Y EX VIVO Ester Risco, Carlos Miguelez, Eduardo Sanchez de Badajoz y Alberto Rouseaud.Arch. Esp. Urol. 2010; 63 (6)
2. TREATMENT OF PAEDIATRIC URINARY INFECTIONS WITH CONCENTRATED CRANBERRY. 1 year follow up. Dr. Garat. Acta pediatrica (in press)

Studies Using Cysticlean

1. Preclinical and clinical studies demonstrated that Cysticlean has an anti-adhesive effect on E coli on the inner bladder wall of up to 83%. This is the key factor for assessing the performance of cranberry extract supplements. Our data on file indicates that the level of cranberry extract alone is not the only indicator affecting the effectiveness in preventing urinary low tract infections but more importantly the level of PAC Type A

Sources
* EFFECT OF CRANBERRY (CYSTICLEAN) ON THE ADHERENCE CAPACITY OF ESCHERICHIA COLI TO EPITHELIAL CELLS OF THE URINARY INNER BLADDER WALL. AN IN VITRO AND EX VIVO STUDY, Arch. Esp. Urol. 2010; 63 (6), Ester Risco, Carlos Miguelez, Eduardo Sanchez de Badajoz y Alberto Rouseaud.
* IN VITRO EVALUATION STUDY OF E. COLI ADHESION TO T24 CELLS, Harlan Laboratories Study S24908
* IN VITRO EVALUATION STUDY OF E. COLI ADHESION TO T24 CELLS, Harlan Laboratories Study S25516

2. Several human observational studies with Cysticlean, with over 500 women participating has indicated up to 80% reduction in the number of urinary infections experienced, with no side effects. Details below:

3. Currently there is a trial running with 500 patients, living in a nursing home who are 65 years of age and older. It is a double blind, placebo controlled trial with continuous treatment using Cysticlean over a period of 6 months .The trial is to evaluate if the recurrence of urinary infections decreases with the continuous use of Cysticlean. This is the first study involving the largest number of elderly patients to demonstrate the effect of Cranberry on urinary tract infection. The study started late 2010 and more than 150 patients are already under treatment. This study will help to confirm the use of Cystilcean in these patients, helping them to reduce their urinary infections and reducing the consumption of antibiotics needed to treat this disease.

Other Facts about Cysticlean

• Doctors and urologists in Europe prescribe and recommend Cysticlean. Dr Rousaud, the well-respected Urologist at the Technology Medical institute in Barcelona says, 'Cysticlean has produced excellent results-the recurrence has decreased dramatically and patients are very satisfied'
• Proven to be safe and effective with now over 300,000 packs sold.
• Recent UK Testimonials can be found at www.cysticlean.co.uk